DAO Enzyme contains a purified form of diamine oxidase (DAO), the primary enzyme responsible for breaking down dietary histamine in the gut before it enters systemic circulation. By supporting histamine
degradation at the intestinal barrier, DAO enzyme helps to alleviate histamine reactions from dietary triggers. This formula is highly concentrated, delivering 30,000 Histamine Degrading Units (HDUs) per capsule for effective histamine balance.
DAO is responsible for the degradation of histamine-containing foods. Highly expressed in the intestinal mucosa, it is most active in the small intestine and is also present in the colon, kidneys, thymus, and placenta. Released into the intestinal lumen, DAO serves as a crucial protective barrier that metabolizes dietary histamine before it can be absorbed into the bloodstream.
Clinical Applications
- Supports healthy DAO enzyme activity in the digestive tract
- Promotes balanced histamine levels in response to dietary triggers
Histamine is a biogenic amine derived from histidine and functions as a neurotransmitter, immune mediator, and local signaling molecule. It interacts with various receptors (H1–H4), leading to effects like vasodilation, inflammation, smooth muscle contraction, and sensory nerve stimulation. Histamine is present within most bodily tissues and can be synthesized in large amounts by white blood cells.
Histamine is not only produced in the body but is present in a wide range of foods produced by bacteria that decarboxylate histidine into histamine. Foods prone to high histamine content include aged or fermented products and refrigerated leftovers. Specifically, matured cheeses, cured or processed meats, fish, and fermented beverages like beer and wine commonly contain elevated histamine levels. Histamine overload may occur after consuming foods with a high histamine content that overwhelms endogenous degradation mechanisms. Even lower histamine amounts found in common food servings can provoke symptoms in sensitive individuals with compromised DAO activity or histaminergic food reactions.
Suggested Use:
1 capsule 15 minutes before a meal or as recommended by your health care professional.
DAO Enzyme by Orthomolecular is not allowed to be sold online
Get Your DAO Enzyme by Orthomolecular Today at Johnson Compounding
If you are looking for professional-grade support for maintaining healthy histamine balance, DAO Enzyme by Orthomolecular provides a concentrated formula designed to support the body’s natural ability to break down dietary histamine. With 30,000 Histamine Degrading Units (HDUs) per capsule, this supplement is designed to be taken before meals to support healthy histamine levels in response to dietary triggers.
DAO Enzyme by Orthomolecular is not available for purchase online and must be ordered directly through Johnson Compounding & Wellness. Contact our team today at 781-893-3870 ext. 3 or stop by our location to learn more and place your order. Our knowledgeable staff is here to help you find the right wellness solutions to support your health goals.
